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. 2022 Oct 1;8:403. doi: 10.1038/s41420-022-01119-w

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — A OTUD1 expression in PC-9/ER and PC-9 cells determined by RT-qPCR. B Transduction efficiency of oe-OTUD1 in PC-9/ER cells and sh-OTUD1 in PC-9 cells determined by RT-qPCR. C IC50 value of erlotinib in oe-OTUD1-treated PC-9/ER cells and sh-OTUD1-treated PC-9 cells determined by CCK-8 assay. D Clonogenic potential of oe-OTUD1-treated PC-9/ER cells and sh-OTUD1-treated PC-9 cells determined by colony formation assay. E Apoptosis rate of oe-OTUD1-treated PC-9/ER cells and sh-OTUD1-treated PC-9 cells measured by flow cytometry. *p < 0.05, **p < 0.01, ***p < 0.001. Data are shown as mean ± standard deviation of three technical replicates. Data between two groups were compared by unpaired t test.