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. Author manuscript; available in PMC: 2023 Aug 1.
Published in final edited form as: Neuroscientist. 2022 Apr 2;29(4):445–460. doi: 10.1177/10738584221082620

Figure 6. Transcriptional Regulation of Astrocyte Function.

Figure 6.

A) Expression dynamics of transcription factors that regulate the generation of neuronal and glial fates in the developing and adult CNS.

B) Patterned expression of development transcription factors Pax6 and Nkx6.1 in subsets of astrocytes in the developing spinal cord.

C) Summary of region specific transcriptional dependencies for NFIA and Sox9. NFIA and Sox9 are universally expressed in astrocytes throughout the brain, but when knocked out specifically impact astrocyte function and associated circuits in a region specific manner.