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Compounds inhibit polyprotein substrate cleavage by SARS-2-PLpro
(A) Polyprotein cleavage assay performed with 1 mM protease and 5 μg of substrate protein. Arrows point at cleavage products.
(B) Cleavage assay performed in the presence of 200 μM of compounds 1, 2, and 3. untr: untreated.
