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. Author manuscript; available in PMC: 2022 Oct 2.
Published in final edited form as: Toxicol Lett. 2020 Dec 5;338:67–77. doi: 10.1016/j.toxlet.2020.12.002

Figure 2.

Figure 2.

Validation of the cysteine and lysine peptide depletion assays. Linear response of cysteine (A) and lysine (B) peptide calibration standards detected by the RapidFire-MS/MS system. Stability of cysteine (C) /lysine (D) peptide mixed alanine peptide up to 30 h (n=6). Concentration response curves of (E) MDG- and (F) hydroquinone-induced cysteine/lysine peptide depletion. The percentage of free cysteine/lysine peptide was normalized based on positive and negative controls and plotted as average ± SD (n=3).