Table 3.

Logistic regression models for matched cohorts

	Comparison #1 (C1)
	OR	95% CI	p
Hospitalization (NO TWO2 vs. TWO2)	8.667	(3.101, 24.219)	<0.0001
Amputation (NO TWO2 vs. TWO2)	4.887	(1.840, 12.985)	0.0015

Study outcomes were assessed through logistic regression models for propensity score–matched cohorts in Comparison #1 (C1). C1 compares patients who ever received TWO2 (TWO2) to those who never received TWO2 (NO TWO2). Patients in both cohorts may have also received other adjunctive therapy. Propensity score matching was performed on the following 9 factors; age, sex, ethnicity, wound severity, prior amputation, use of offloading, use of NPWT, use of SS, use of GF.

CI, confidence interval; OR, odds ratio.