Figure 4.
3D visualization of ligands docked against ESR1 and ACAA1. LIMO-generated ligands (one for each protein) are shown in yellow, and raloxifene, a cancer drug that targets ESR1, is shown in pink. The protein pocket is displayed as semi-opaque, and nearby structures of the protein are shown in blue. Docked poses were generated by GLIDE (Friesner et al., 2004) for ESR1 and AutoDock-GPU (Santos-Martins et al., 2021) for ACAA1. Favorable atom-atom interactions between ligand and protein are shown with a dashed yellow line.