TABLE 3.
Characterization of genes differentially regulated in P. gingivalis PLM1
| Gene product (GenBank accession no.) | Homologous proteina (reference) | Function | Expression in luxS mutant |
|---|---|---|---|
| HemR (AAC44980) | P. gingivalis hemin-regulated outer membrane protein (22) | TonB-dependent receptor | Absent |
| Excinuclease ABC homologue (P14951) | B. subtilis excision nuclease (6) | DNA repair | Absent |
| Outer membrane protein (BAA88494) | P. fluorescens heme acquisition protein (19) | Hemin uptake | Present |
| RgpA (A55426) | P. gingivalis arginine-specific protease (31) | Multiple, including provision of hemin by degradation of hemin-sequestering proteins | Present |
| TonB homologue (E82955) | Pseudomonas siderophore acquisition protein (33) | Energy transducer | Absent |
a
Determined by comparison with sequences of the GenBank database.