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. 2022 Oct 15;209(8):1492–1498. doi: 10.4049/jimmunol.2200307

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Copyright © 2022 by The American Association of Immunologists, Inc.

This article is distributed under The American Association of Immunologists, Inc., Reuse Terms and Conditions for Author Choice articles.

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FIGURE 3. — Enrichment of histone H3K27me3 and H3K9/K14ac in the miR-1246 promoter in SLE B cells. (A–C) ChIP-qPCR analysis of the enrichment of histone H3K27me3 (A) and H3K9/K14ac (B and C) in the miR-1246 promoter of B cells isolated from SLE patients or healthy controls (n = 20 for each group). The results are presented relative to those obtained with input DNA prepared from untreated chromatin. (D) Correlation between histone H3K27me3 enrichment and miR-1246 expression level (n = 20). (E) The correlation between histone H3K9ac enrichment and miR-1246 expression level (n = 20). (F) Correlation between histone H3K14ac enrichment and miR-1246 expression level (n = 20). **p < 0.01.