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. 2022 Sep 19;13:1012548. doi: 10.3389/fgene.2022.1012548

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Copyright © 2022 Bao, Zhu, Fan, Ye, Li and Chai.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Kaplan−Meier survival analysis of patients with osteosarcoma (n = 42). (A) Correlation of the SPAG6 protein expression level with the overall survival time of patients with osteosarcoma. The y-axis represents the percentage of patients, the x-axis represents their survival in months, and the green line represents SPAG6⁺ patients with a worse survival trend than the blue line representing SPAG6^- (p < 0.05). (B) Correlation of the NM23 protein expression level with the overall survival time of patients with osteosarcoma, and the green line represents NM23⁺ patients with a better survival trend than the blue line representing NM23^- patients (p < 0.05).