TABLE 2.
Top 20 differential metabolites between responders and non-responders ranked by the area under the receiver operating characteristic curve (AUC).
| No. | Differential metabolites | AUC | FDR | Log2 FC |
|---|---|---|---|---|
| 1 | LPC 18:0 sn-1 | 0.896 | 2.650 × 10^-18 | 0.451 |
| 2 | LPC 16:0 sn-1 | 0.892 | 5.321 × 10^-17 | 0.449 |
| 3 | LPC 16:0 sn-2 | 0.876 | 8.154 × 10^-16 | 0.454 |
| 4 | PC 38:6 | 0.832 | 1.706 × 10^-12 | 0.465 |
| 5 | SM 34:1 | 0.829 | 4.252 × 10^-12 | 0.383 |
| 6 | LPC 18:1 sn-1 | 0.827 | 3.679 × 10^-11 | 0.323 |
| 7 | PC 34:0 | 0.819 | 4.700 × 10^-11 | 0.380 |
| 8 | PC 34:1 | 0.813 | 1.561 × 10^-10 | 0.415 |
| 9 | PC 38:5 | 0.798 | 3.192 × 10^-8 | 0.477 |
| 10 | PC 36:3 | 0.795 | 4.843 × 10^-9 | 0.363 |
| 11 | PC O-38:6 | 0.785 | 4.852 × 10^-8 | 0.414 |
| 12 | PC 36:2 | 0.784 | 5.403 × 10^-9 | 0.482 |
| 13 | LPE 22:6 sn-1 | 0.784 | 1.147 × 10^-8 | 0.525 |
| 14 | PC O-38:5 | 0.780 | 6.600 × 10^-8 | 0.357 |
| 15 | LPC 18:2 sn-1 | 0.779 | 5.813 × 10^-8 | 0.390 |
| 16 | PE O-38:7 | 0.778 | 2.551 × 10^-8 | 0.589 |
| 17 | PC O-36:5 | 0.777 | 4.371 × 10^-8 | 0.426 |
| 18 | LPC O-16:1 | 0.772 | 3.866 × 10^-9 | 0.382 |
| 19 | PC 38:4 | 0.770 | 3.016 × 10^-7 | 0.466 |
| 20 | LPC 16:1 sn-1 | 0.767 | 1.701 × 10^-8 | 0.459 |
AUC, area under the receiver operating characteristic curve; FDR, false discovery rate; FC, fold change.