Table 1.
Functional analysis of the intersected DEGs.
| Category | Term | Count | Fold enrichment | P value |
|---|---|---|---|---|
| GOTERM_BP_FAT | GO: 0006350∼transcription | 26 | 1.455737434 | 0.0433219 |
| GOTERM_BP_FAT | GO: 0010605∼macromolecule metabolic process | 15 | 2.403980571 | 0.0034352 |
| GOTERM_BP_FAT | GO: 0006357∼transcription from RNA polymerase II promoter | 14 | 2.26531906 | 0.0081237 |
| GOTERM_BP_FAT | GO: 0010604∼positive regulation of macromolecule metabolic process | 14 | 1.921688397 | 0.0280958 |
| GOTERM_BP_FAT | GO: 0016265∼death | 13 | 2.11222676 | 0.0188254 |
| GOTERM_BP_FAT | GO: 0010558∼negative regulation of macromolecule biosynthetic process | 12 | 2.580653366 | 0.0063959 |
| GOTERM_BP_FAT | GO: 0031327∼negative regulation of cellular biosynthetic process | 12 | 2.516252034 | 0.007676 |
| GOTERM_BP_FAT | GO: 0009890∼negative regulation of biosynthetic process | 12 | 2.463555657 | 0.0089258 |
| GOTERM_BP_FAT | GO: 0006915∼apoptosis | 12 | 2.344879388 | 0.0126006 |
| GOTERM_BP_FAT | GO: 0012501∼programmed cell death | 12 | 2.310339429 | 0.0139488 |
| GOTERM_CC_FAT | GO: 0070013∼intracellular organelle lumen | 23 | 1.530125122 | 0.0368931 |
| GOTERM_CC_FAT | GO: 0043233∼organelle lumen | 23 | 1.495655271 | 0.0458439 |
| GOTERM_CC_FAT | GO: 0031981∼nuclear lumen | 21 | 1.714061303 | 0.0165472 |
| GOTERM_CC_FAT | GO: 0016323∼basolateral plasma membrane | 6 | 3.498084291 | 0.0278083 |
| GOTERM_CC_FAT | GO: 0000123∼histone acetyltransferase complex | 5 | 11.83518519 | 7.95E-04 |
| GOTERM_CC_FAT | GO: 0016591∼DNA-directed RNA polymerase II, holoenzyme | 5 | 7.305669867 | 0.0047125 |
| GOTERM_CC_FAT | GO: 0005912∼adherens junction | 5 | 3.817801673 | 0.0411102 |
| GOTERM_CC_FAT | GO: 0033276∼transcription factor TFTC complex | 3 | 25.36111111 | 0.0059162 |
| GOTERM_CC_FAT | GO: 0005669∼transcription factor TFIID complex | 3 | 16.13888889 | 0.0143787 |
| GOTERM_CC_FAT | GO: 0070461∼SAGA-type complex | 3 | 15.43719807 | 0.015663 |
| GOTERM_MF_FAT | GO: 0003677∼DNA binding | 29 | 1.495570968 | 0.021546 |
| GOTERM_MF_FAT | GO: 0030528∼transcription regulator activity | 22 | 1.749130413 | 0.0110444 |
| GOTERM_MF_FAT | GO: 0003700∼transcription factor activity | 16 | 1.972725546 | 0.0136976 |
| GOTERM_MF_FAT | GO: 0003712∼transcription cofactor activity | 8 | 2.649321498 | 0.030379 |
| GOTERM_MF_FAT | GO: 0005525∼GTP binding | 8 | 2.58522501 | 0.0340327 |
| GOTERM_MF_FAT | GO: 0019001∼guanyl nucleotide binding | 8 | 2.517548963 | 0.0384249 |
| GOTERM_MF_FAT | GO: 0032561∼guanyl ribonucleotide binding | 8 | 2.517548963 | 0.0384249 |
| GOTERM_MF_FAT | GO: 0016564∼transcription repressor activity | 7 | 2.662945382 | 0.0464633 |
| GOTERM_MF_FAT | GO: 0003713∼transcription coactivator activity | 6 | 3.370456906 | 0.0319331 |
| GOTERM_MF_FAT | GO: 0004468∼lysine N-acetyltransferase activity | 4 | 12.6539961 | 0.0037232 |
| GOTERM_MF_FAT | GO: 0003677∼DNA binding | 29 | 1.495571 | 0.021546 |
| GOTERM_MF_FAT | GO: 0030528∼transcription regulator activity | 22 | 1.74913 | 0.011044 |
| GOTERM_MF_FAT | GO: 0003700∼transcription factor activity | 16 | 1.972726 | 0.013698 |
| GOTERM_MF_FAT | GO: 0003712∼transcription cofactor activity | 8 | 2.649321 | 0.030379 |
| GOTERM_MF_FAT | GO: 0005525∼GTP binding | 8 | 2.585225 | 0.034033 |
| GOTERM_MF_FAT | GO: 0019001∼guanyl nucleotide binding | 8 | 2.517549 | 0.038425 |
| GOTERM_MF_FAT | GO: 0032561∼guanyl ribonucleotide binding | 8 | 2.517549 | 0.038425 |
| GOTERM_MF_FAT | GO: 0016564∼transcription repressor activity | 7 | 2.662945 | 0.046463 |
| GOTERM_MF_FAT | GO: 0003713∼transcription coactivator activity | 6 | 3.370457 | 0.031933 |
| GOTERM_MF_FAT | GO: 0004468∼lysine N-acetyltransferase activity | 4 | 12.654 | 0.003723 |
| KEGG_PATHWAY | hsa05200: Pathways in cancer | 9 | 2.847498756 | 0.0107241 |
| KEGG_PATHWAY | hsa04510: Focal adhesion | 6 | 3.097776424 | 0.0396646 |
| KEGG_PATHWAY | hsa04910: Insulin signaling pathway | 5 | 3.843537415 | 0.0375672 |
| KEGG_PATHWAY | hsa04210: Apoptosis | 5 | 5.964109782 | 0.0087712 |
| KEGG_PATHWAY | hsa04130: SNARE interactions in vesicular transport | 3 | 8.192803437 | 0.049457 |
DEGs, differential expressed genes.