Abnormal uterine bleeding (AUB)	Implicitly, non-gestational and in the reproductive years. Any alteration in the normal frequency, regularity, duration or volume of menstrual bleeding (including HMB) as well as intermenstrual bleeding and unscheduled bleeding with pharmaceutical agents designed to suppress menstrual function
Acute heavy menstrual bleeding	An episode of HMB of sufficient volume to require immediate therapy
Amenorrhea	A symptom—absence of menstrual bleeding in a girl or woman in the reproductive years
Anovulation	Failure to ovulate
Chronic abnormal uterine bleeding (AUB)	Symptoms of AUB for the majority of the past 6 months
Chronic ovulatory disorder	Evidence of an ovulatory disorder for the majority of the previous 6 months
Frequent menstruation	An AUB symptom—menstrual cycle of less than 24 days
Heavy menstrual bleeding (HMB)	An AUB symptom—excessive menstrual blood loss that interferes with a woman’s physical, social, emotional and/or material quality of life
Infrequent menstruation	An AUB symptom—menstrual cycle length of more than 38 days
Intermenstrual bleeding	An AUB symptom—uterine bleeding between regular menstrual periods
Irregular menstruation	An AUB symptom—menstrual cycle lengths that vary by more than 7 (ages of 18–25 and 42–45 years) to 9 days (ages of 26–41 years)
Luteinized unruptured follicle (LUF)	Physical failure of follicle rupture (oocyte release), with the luteinization and other endocrine features of the secretory phase of the menstrual cycle
Luteal out of phase (LOOP) event	Premature recruitment of a follicle in the luteal phase of a menstrual cycle
Menstrual cycle	The duration in days from the first day of one menstrual period to the first day of the next
Ovulation	The release of an oocyte (egg) from an ovarian follicle
Ovulatory disorder	Any alteration of ovulatory function in non-pregnant women in the usual reproductive years
Primary amenorrhea	Failure of onset of menstruation by the age of 15 years
Prolonged menstruation	An AUB symptom—a menstrual period lasting more than 8 days
Secondary amenorrhea	Absence of menstrual periods for more than 180 days in an individual who has had at least one spontaneous menses