Table 3. Apparent Michaelis constants in the direction of succinyl-CoA synthesis.

	Substrate concentrations
Human GTPSCS	Succinate (mM)	CoA (µM)	GTP (µM)	Varied substrate	(µM)
Wild type	50	100	1.875–120.000	GTP	3.4 ± 0.2
	0.039–5.000	100	100	Succinate	20 × 101 ± 1 × 101
	50	0.664–80.000	100	CoA	1.6 ± 0.2
E105αQ	50	100	1.875–120.000	GTP	7.1 ± 0.6
	1.25–50.00	100	100	Succinate	101 × 102 ± 6 × 102
	50	2.656–85.000	100	CoA	18 ± 1