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. 2022 Oct 3;12:16522. doi: 10.1038/s41598-022-20263-y

Table 1.

Description of the variables used in the models of precocity and severity of COVID-19 (April–October 2020).

Source: Sub-National COVID-19 Incidence and Determinants Dataset.

Variable Description Spatial scope* Time scope
Weekly deaths (dependent variable) COVID-19 related weekly deaths Subnational Weekly
International mobility
Incoming passengers Total incoming airline passengers in NUTS2 region, lagged by 1 month Subnational Monthly
Importation risk COVID-19 related weekly deaths per capita in NUTS2 sending regions weighted by share of total incoming passengers from each region, lagged by 1 month Subnational Monthly
Airport centrality Eigenvector centrality of airports in international travel network, where edges are weighted by number of passengers (median of airports in region), lagged by 1 month Subnational Monthly
Absence of airports No airport in the region (dummy variable) Subnational Time-invariant
Travel restrictions
None/minimal No travel ban or only screening and/or quarantining at arrival, lagged by 3 weeks National Weekly
Partial bans Ban on arrivals from certain regions, lagged by 3 weeks National Weekly
Total ban Ban on all regions or total border closure, lagged by 3 weeks National Weekly
Local factors
Population Size of resident population Subnational Time-invariant
Oxford-tracker stringency index (modified) Index summarizing containment and closure policies including: school closure, workplace closing, cancelling of public events, restrictions on gatherings, closing of public transport, stay at home requirements and restrictions on internal movement; not containing air travel policies, lagged by 3 weeks National Weekly
Real GDP pc PPP Real GDP per capita PPP at constant prices (millions of USD) Subnational Time-invariant
Population density Population per km2 Subnational Time-invariant
Hospital beds per 1000 Hospital beds per 1000 inhabitants National Time-invariant
Share of 65 + Share of population of age 65 or over (%) Subnational Time-invariant
Cardiovascular death rate Age-standardized deaths from cardiovascular diseases per 100 k inhabitants National Time-invariant
Cancer death rate Age-standardized deaths from cancer per 100 k inhabitants National Time-invariant
Prevalence of adult obesity Percentage of adults aged 18 and over with Body Mass Index (BMI) of 30 kg/m2 or higher National Time-invariant
Week of first COVID death Week of the year in which first COVID-related death was recorded Subnational Time-invariant

*The subnational level corresponds to the NUTS2 level in Europe and comparable administrative regions in non-European countries (e.g., in the US corresponding to Federal States).