. Author manuscript; available in PMC: 2022 Oct 3.

Published in final edited form as: Sci Transl Med. 2020 Nov 4;12(568):eaay5067. doi: 10.1126/scitranslmed.aay5067

Table 2:

AUROCs for prediction of antibiotic non-susceptibility in patients presenting with uncomplicated UTI between 2014 and 2016.

	AUROC (95% CI)^a
Drug^b	Full test cohort	Prior antibiotic resistance or exposure
Nitrofurantoin	0.56 (0.53, 0.59)	0.61 (0.55, 0.66)
TMP-SMX	0.59 (0.57, 0.62)	0.67 (0.64, 0.71)
Ciprofloxacin	0.64 (0.60, 0.68)	0.76 (0.71, 0.80)
Levofloxacin	0.64 (0.60, 0.68)	0.77 (0.71, 0.82)

AUROC and 95% CI calculated using 1000 bootstrapped samples taken from the test set.

Logistic regression was chosen for prediction for all four antibiotics.