Table 3.

Self-report data outcomes. Group means are values after imputation. [Diff.=difference (estimated marginal mean); SD=standard deviation; MHC=mental healthcare; SAU=service as usual; INT=integrated intervention; BDI=Bech Depression Inventory; BAI=; PSS=Perceived Stress Scale; WSAS=Work and Social Adjustment Scale; 4DSQ=Four Dimensional Questionnaire; KEDS=Karolinska Exhaustion Disorder Scale; IPQ=Illness Perception Questionnaire; EQ5DL=health-related quality of life; QoLs=Quality of Life Scale; RTW-SE=return to work-self efficacy; SPS=Stepford Presenteeism Scale; GSE=Generalized Self-Efficacy Scale; CSQ=The Client Satisfaction Questionnaire]

Outcome domain	Outcome Secondary (S) Exploratory (E)	Group comparisons
		SAU - MHC		SAU - INT		MHC - INT
		Diff	P-value (98.3%CI)	Diff	P-value (98.3%CI)	Diff	P-value (98.3%CI)
		6-month follow-up
		Symptoms	BAI (S)	2.16	0.0051 a (0.32–4.01)	1.23	0.122 (-0.67–3.13)	-0.97	0.199 (-2.79–0.84)
	BDI (S)	1.37	0.112 (-0.7–3.44)	0.52	0.548 (-1.55–2.59)	-0.84	0.316 (-2.85–1.17)
	PSS (S)	1.83	0.0055 a (0.26–3.41)	0.43	0.506 (-1.13–2)	-1.40	0.0261 b(-2.91–0.11)
	KES (E)	5.24	0.0007 a (1.57–8.91)	3.04	0.0445 b(-0.59–6.67)	-2.20	0.133 (-5.7–1.31)
	4DSQ-somatization (E)	1.28	0.0402 b (-0.21–2.77)	0.97	0.136 (-0.59–2.52)	-0.36	0.544 (-1.76–1.05)
	4DSQ-distress (E)	1.41	0.0365 b (-0.21–3.03)	1.06	0.114 (-0.55–2.68)	-0.33	0.604 (-1.88–1.21)
	4DSQ-anxiety (E)	0.70	0.065 (-0.21–1.6)	0.55	0.14 (-0.34–1.43)	-0.17	0.64 (-1.03–0.7)
	4DSQ-depression (E)	0.14	0.527 (-0.38–0.66)	-0.06	0.788 (-0.6–0.48)	-0.19	0.4 (-0.73–0.35)
Functioning	WSAS (S)	2.11	0.0234 b (-0.12–4.33)	0.99	0.28 (-1.2–3.18)	-1.13	0.195 (-3.22–0.96)
Presenteeism	SPS (E)	0.13	0.675 (-0.62–0.89)	0.12	0.682 (-0.6–0.85)	0.00	0.99 (-0.67–0.66)
Self-efficacy	IPQ (E)	-0.09	0.801 (-1–0.81)	-0.31	0.409 (-1.21–0.59)	-0.20	0.585 (-1.07–0.67)
	GSE (E)	-0.30	0.632 (-1.82–1.22)	0.53	0.411 (-1.01–2.07)	0.83	0.187 (-0.68–2.35)
	RTW-SE (E)	-0.47	0.588 (-2.53–1.6)	-0.20	0.811 (-2.25–1.84)	0.30	0.713 (-1.67–2.28)
Life quality	QoL (E)	-0.10	0.94 (-3.24–3.04)	0.53	0.682 (-2.6–3.67)	0.60	0.636 (-2.45–3.65)
	EQ5 (E)	-0.02	0.166 (-0.05–0.01)	0.00	0.787 (-0.03–0.03)	0.01	0.246 (-0.02–0.04)
Satisfaction	CSQ (E)	-2.68	<0.0005 a (-4.12–-1.24)	-2.86	<0.0005 a(-4.29–-1.43)	-0.18	0.744 (-1.49–1.14)
12-month follow-up
Symptoms	BAI (E)	1.32	0.084 (-0.51–3.14)	1.03	0.184 (-0.83–2.9)	-0.31	0.676 (-2.09–1.47)
	BDI (E)	-0.20	0.819 (-2.28–1.88)	-0.49	0.563 (-2.53–1.55)	-0.27	0.747 (-2.28–1.74)
	PSS (E)	0.38	0.57 (-1.23–2)	0.50	0.456 (-1.11–2.12)	0.12	0.857 (-1.49–1.73)
	KES (E)	3.56	0.0233 b(-0.2–7.31)	2.28	0.147 (-1.49–6.04)	-1.27	0.412 (-4.98–2.44)
	4DSQ-somatization (E)	0.92	0.139 (-0.57–2.41)	0.89	0.163 (-0.64–2.42)	-0.07	0.911 (-1.48–1.35)
	4DSQ-distress (E)	0.45	0.503 (-1.17–2.07)	0.44	0.507 (-1.16–2.05)	0.01	0.994 (-1.6–1.61)
	4DSQ-anxiety (E)	0.47	0.196 (-0.4–1.33)	0.42	0.233 (-0.43–1.27)	-0.05	0.874 (-0.88–0.77)
	4DSQ-depression (E)	-0.31	0.144 (-0.83–0.2)	-0.18	0.41 (-0.7–0.34)	0.14	0.521 (-0.39–0.68)
Functioning	WSAS (E)	0.05	0.955 (-2.18–2.29)	-0.22	0.812 (-2.45–2.01)	-0.28	0.754 (-2.42–1.86)
Presenteeism	SPS (E)	0.03	0.932 (-0.9–0.97)	-0.32	0.397 (-1.21–0.58)	-0.31	0.375 (-1.15–0.53)
Self-efficacy	IPQ (E)	-0.03	0.936 (-0.96–0.9)	-0.22	0.578 (-1.19–0.74)	-0.18	0.649 (-1.1–0.75)
	GSE (E)	0.08	0.898 (-1.45–1.61)	0.97	0.138 (-0.6–2.54)	0.90	0.161 (-0.64–2.44)
	RTW-SE (E)	-0.16	0.858 (-2.26–1.95)	-0.04	0.963 (-2.14–2.06)	0.16	0.857 (-1.9–2.21)
Life quality	QoL (E)	1.28	0.327 (-1.85–4.41)	0.65	0.616 (-2.45–3.74)	-0.65	0.61 (-3.71–2.41)
	EQ5 (E)	-0.01	0.468 (-0.04–0.02)	0.00	0.993 (-0.03–0.03)	0.01	0.452 (-0.02–0.04)

^aP≤0.0167.

^b0.05 ≤P< 0.0167.