Table 4.
Univariable and Multivariable Analysis of Factors Associated with PFS
| Characteristic | Univariable Analysis | Multivariable Analysis | ||
|---|---|---|---|---|
| Hazard Ratio (95% CI) | P value | Hazard Ratio (95% CI) | P value | |
| ECOG-PS (0–1 vs 2–4) | 2.46 (1.59–3.79) | <0.001 | 2.84 (1.82–4.42) | <0.001 |
| Lines of therapy (<2 vs ≥2) | 1.68 (1.08–2.62) | 0.022 | ||
| HR status (HR- vs HR+) | 1.44 (0.99–2.10) | 0.058 | 1.56 (1.07–2.27) | 0.022 |
| HER2 status (IHC3+ vs IHC2+andFISH+) | 1.32 (0.83–2.12) | 0.242 | ||
| Visceral metastases (no vs yes) | 1.46 (0.94–2.27) | 0.093 | 1.74 (1.11–2.73) | 0.016 |
| Bone metastases (no vs yes) | 1.42 (0.97–2.07) | 0.072 | ||