B. anthracis LT attenuates PMN accumulation at sites of infection.
A. Comparison of left-ear luminescence over background between PMA-treated mice and mice that were injected subcutaneously with 3 × 106 cfu of vegetative TKO. No significant differences were seen at any time point.
B. Comparison between NECre luc mice which were subcutaneously injected with 3 × 106 cfu of TKO, with and withouti.p. injection of 6.25 μg LT, and NECre luc mice injected subcutaneously with 3 × 106 cfu of vegetative EF knockout B. anthracis. Significant differences were seen between TKO and EF knockout injected mice at 48 h post injection (**P < 0.05). n = 4 mice for each experimental group (A and B).