. Author manuscript; available in PMC: 2022 Oct 3.

Published in final edited form as: Cell Microbiol. 2013 Nov 6;16(4):504–518. doi: 10.1111/cmi.12232

Table 2.

LF levels increase in all major organs over time during B. anthracis infection.

Sample	Early infection^a	Mid infection^a	Late infection^a
Serum^c	0.894 ± 0.550	27.32 ± 18.18	1973±1725
Infected ear^d	16.25 ± 14.32	94.25 ± 63.05	1201 ± 207.4
Control ear^d	0.099 ± 0.054	0.569 ± 0.336	28.75 ± 14.28
Infected lymph node^d	0.253 ± 0.253	547.5 ± 183.6	5057 ± 2889
Control lymph node^d	< LOD^b	2.626 ± 1.816	868.4 ± 575.3
Heart^d	0.043 ± 0.043	16.70 ± 15.23	382.3 ± 343.7
Lungs^d	0.044 ± 0.032	5.865 ± 5.160	601.1 ± 497.6
Spleen^d	0.041 ± 0.041	2.606 ± 1.717	1115 ± 895.9
Liver^d	0.008 ± 0.004	9.057 ± 8.622	895.7 ± 611.0
Right bone marrow^c	< LOD^b	0.145 ± 0.100	27.68 ± 24.42
Left bone marrow^c	< LOD^b	0.132 ± 0.088	22.27 ± 17.10
Brain^d	< LOD^b	0.092 ± 0.066	60.25 ± 41.73

^a.

Injection of 1 × 10⁵ spores of luminescent 7702 (BIG23) spores subcutaneously into the left ear of three A/J mice. Samples were collected and processed when mice reached the indicated stage of infection.

^b.

Samples where potential LF concentrations are below the limit of detection (LOD).

^c.

Samples reported in ng ml⁻¹ ± standard error of the mean.

^d.

Samples reported in ng g⁻¹ of tissue standard ± error of the mean.