Figure 1.

Physicochemical characterisation of Gel MS, Gel-HA MS and CDHA MS. (a) SEM images of the MS and high-magnification in the insets showing their surface. (b) Size distribution of the different MS, in both dry and wet conditions. The MS were sieved from 40 to 100 µm before the measurement, the grey area represents the sieving applied. (c) ATR-FTIR spectra of the synthesised MS, along with the spectra of the commercial gelatine and the synthesised HA NPs. Stripped and shaded regions correspond to the characteristic bands of gelatine and HA NPs, respectively. (d) X-ray diffraction patterns of Gel-HA MS and CDHA MS. (e) Calcium and phosphorus concentration of the cell culture media in contact with the various MS for 4 days, determined by ICP-OES.