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. 2022 Sep 29;31:09636897221110525. doi: 10.1177/09636897221110525

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© The Author(s) 2022

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 2. — The naïve state of pluripotent stem cells aligns with the best match embryonic stage of development. Mice and human morphologic development are similar through the blastocyst stage, with human development being slower than that of mouse. The naïve stem cells and primed stem cells most resemble the preimplantation blastocyst and postimplantation blastocyst, respectively, for the different species. Human intermediate stem cells fall between the preimplantation and postimplantation blastocyst stage of development.