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. 2022 Oct 3;142:104902. doi: 10.1016/j.neubiorev.2022.104902

Table 3.

Physical performance fatigability assessment instruments used in COVID-19.

Instruments Descriptions Findings in COVID-19
Six-Minute WalkTest(6MWT) Functional capacity test. The main outcome is the assessment of distance traveled(Singh et al. 2014). 147 (12%) of 1248 patients at 1 year after COVID-19 were below the lower limit of normal(L.Huang et al., 2021, Huang et al., 2021).
Incremental Shuttle Walk Test (ISWT) Exercise capacity test, with progressive walking and guided by sound signals. The primary endpoint is the assessment of distance walked(Singh et al. 2014). The average distance for patients with COVID-19 sequelae referred for rehabilitation was 300 (198) meters(EnyaDaynes et al., 2021).
Short Physical Performance Battery (SPPB) Lower-limb physical performance. Evaluation of balance, gait speed and lower limb strength (Guralnik et al., 1994). 53 patients (22.3%) of 238 had impaired physical performance 4 months after hospital discharge for COVID-19(Bellan et al., 2021).
Maximum Voluntary Isometric Contraction Maximal voluntary isometric strength evaluation test(Meldrum et al. 2007). Muscle weakness of the quadriceps and biceps was observed in 86% and 76% of 41 patients without pre-COVID-19 disabilities(Paneroni et al. 2021a).
Hand Grip Dominant hand grip strength test(Bohannon 2015). The mean strength value observed in 73 female patients was 21.83 kg and in 77 male patients was 36.93. For females with a history of severe COVID-19 the grip strength was lower when compared to non-severe cases(Tuzun et al., 2021).
Electromyography Evaluation of muscle electrical activity (Kane and Oware 2012). Of the 20 patients with persistent fatigue from COVID-19, 11 (55%) showed changes in electrical activity compatible with myopathy(Agergaard et al., 2021).