Table 1.
Mouse model poxvirus infections in which efficacy of cidofovir has been demonstrated
| Virus | Route of virus infection | Route of drug administration | Refs |
|---|---|---|---|
| Vaccinia | Intravenous | Subcutaneous | [7] |
| Vaccinia | Intranasal | Subcutaneous or intraperitoneal | 8., 9. |
| Cowpox | Intranasal | Subcutaneous | 10., 11. |
| Cowpox | Intranasal (aerosolized) | Intranasal (aerosolized) | 12., 13. |
| Cowpox | Aerosolized | Oral HDP-HPMPCa | [17] |
a
Abbreviation: HDP–HPMPC, hexadecyloxypropyl-(S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)-cytosine (cidofovir).