Table 1.

Supportive management of monkeypox.

Component of management	Symptoms/Signs	Management
Protection of mucous membrane and compromised skin	Skin rash	•Clean with regular antiseptics
		•Mupironic Acid/Fucidin
		•Light dressing can be used if an extensive lesion is present
		•Try to avoid touching/scratching the lesions
		•In case of secondary infection, relevant systematic antibiotics may be considered
	Genital ulcers	•Slitz bath
	Oral ulcers	•Warm saline gargles/oral, topical anti-inflammatory gel
	Conjunctivitis	•Usually, self-limiting
		•Consult an ophthalmologist if symptoms persist or if there are pain/visual disturbances
Rehydration therapy and nutritional support	Dehydration can occur in association with decreased appetite, nausea, vomiting, and diarrhea	•Use ORS or oral fluids
		•Use intravenous fluids if indicated
		•Take a nutritious and sufficient diet
Symptom alleviation	Fever	•Lukewarm sponging
		•Paracetamol as per requirement
	Itching/Pruritus	•Topical calamine lotion
		•Antihistamines
	Nausea and vomiting	•Use anti-emetics
	Headache/malaise	Paracetamol and sufficient hydration [10]