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. 2022 Aug 11;155:105254. doi: 10.1016/j.jcv.2022.105254

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© 2022 Elsevier B.V. All rights reserved.

Elsevier has created a Monkeypox Information Center (https://www.elsevier.com/connect/monkeypox-information-center) in response to the declared public health emergency of international concern, with free information in English on the monkeypox virus. The Monkeypox Information Center is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its monkeypox related research that is available on the Monkeypox Information Center - including this research content - immediately available in publicly funded repositories, with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the Monkeypox Information Center remains active.

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Fig 1: — Viral DNA-load time courses were plotted for hospitalized patients with available serial measurements. A) Swabs from cutaneous lesions were taken according to established procedures; however, the exact location where swabs were taken has not been recorded. Also, swabbing procedures may entail opening a fresh lesion, which will then crust over. The indicated viral loads represent generic lesion swabs from the respective patient, not necessarily from the same lesion. (1st week: median 3.31E+07 cp/ml, range 2.19E+07 – 3.95E+07 cp/ml; 2nd week: median 3.04E+06 cp/ml, range 2.11E+05 – 5.48E+05 cp/ml). Graphs B) and C) represent oropharyngeal swabs (1st week: median 8.44E+04 cp/ml, range 6.93E+04 – 7.31E+05 cp/ml; 2nd week: median 4.04E+03 cp/ml, range 0 – 6.75E+06 cp/ml; 3rd week: median 0 cp/ml, range 0 – 2.00E+04 cp/ml) and EDTA plasma-samples (1st week: median 5.85E+02 cp/ml, range 1.58E+02 – 1.05E+03 cp/ml; 2nd week: median 7.80E+00 cp/ml, range 0 – 1.20E+03 cp/ml; 3rd week: single sample, 2.37E+01 cp/ml) respectively.