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Flow cytometry analysis of immune subsets in peripheral blood. PBMCs were analyzed for T cell memory populations and PD1 expression on CD8+ and CD4+ conventional T cells as shown at the pretreatment time point. Patients in red have median PFS of 2.3 years after lerapolturev and patients in black have median PFS 1.6 months after lerapolturev. Data brackets indicate mean ±SEM; p values are from unpaired t-test. PBMCs, peripheral blood mononuclear cells; PFS, progression-free survival.
