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. Author manuscript; available in PMC: 2022 Oct 3.
Published in final edited form as: J Bone Miner Res. 2013 Sep;28(9):1962–1974. doi: 10.1002/jbmr.1935

Fig. 4.

Fig. 4.

Reduced bone resorption and bone formation rate in Lrrk1 KO mice. (A) Longitudinal bone sections of L5 of 79-week-old male mice. Bone sections are stained with hematoxylin and eosin. Arrows indicate osteoclasts (OCs) within the areas indicated. (B) Images of calcein double-labeling of the femurs from 8-week-old mice. Mineral apposition rate (MAR) (C) and bone formation rate (BFR) (D) within the areas indicated. Data are means ± SEM for n = 8. Asterisks indicate a significant difference in KO mice compared with WT mice (p < 0.01).