Fig. 1. SARS-CoV-2 RNA and immune infiltration are present in adipose tissue of autopsy samples from patients with COVID-19.
(A to E) RNA in situ hybridization (ISH) on epicardial fat from heart autopsies from patients with COVID-19 are shown. (A and B) show samples from autopsy #9. (C to E) show samples from autopsy #10. Assays were performed using probes against SARS-CoV-2 spike mRNA. Black arrowheads show ISH positive signals and gray arrows show inflammatory cells. (A and C) Overview of the heart tissue section (2mm), and (B and D) magnified view (20μm) of the represented region. (E) Interface of epicardial fat and myocardium (50μm). Note the inflammatory infiltration (gray arrows) only in the epicardial fat. Image has been rotated 90°.