TABLE 1.

Experiences clinical trial sites during site selection13

SITE QUALITY	QUESTION	YES (%)	NO (%)
Clinical trials experience/ Interest and commitment	Have you experienced that your company selected/recommended an inexperienced trial site in favor of an experienced trial site during site selection due to a higher level of interest and commitment?	52	48
Interest and commitment	Have you experienced that your company selected/recommended a trial site unknown to your company in favor of a well-known trial site due to a higher level of interest and commitment?	57	43
Timely patient recruitment/Key opinion leader	Have you experienced that your company selected/recommended a trial site despite an insufficient recruitment in prior trials, because a key opinion leader was associated with the site?	63	37
Timely patient recruitment	Have you experienced that your company deselected/did not recommend a trial site that delivered a timely patient recruitment in prior trials, because your company found it difficult to cooperate with the site in those prior trials?	53	47
Costs at the site*	Have you experienced that the trial sites selected by the affiliate(s) were not approved by the headquarters because the costs of running the trial, at the trial sites were too high?	37	63
Costs at the site†	Have you experienced that your company did not recommend trial sites to a sponsor because the costs of running the trial at the trial sites were too high?	25	75

^*This question only applied to biopharmaceutical respondents (n=43).

^†This question only applied to clinical research organization respondents (n=40).

From: Dombernowsky et al. Criteria for site selection in industry-sponsored clinical trials: a survey among decision-makers in biopharmaceutical companies and clinical research organizations. Trials. 2019;20:708.