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. 2022 Sep;33(9):1708–1725. doi: 10.1681/ASN.2021111425

Figure 4.

Figure 4.

CDYL-mediated histone Kcr modulates the expression of CDYL target genes. (A) Heatmaps showing the occupancy of TY1-CDYL and PanKcr on CDYL target genes in control and CDYL OE WT 9-12 cells. (B and C) PanKcr ChIP-seq signal density in three gene clusters based on TY1-CDYL ChIP-seq signal density on CDYL target genes. (D) Representative integrative genomics viewer tracks showing PanKcr ChIP-seq signal on high, medium, and low TY1-CDYL-binding loci. (E) Pearson’s correlation coefficient of PanKcr ChIP-seq signals and gene expression in CDYL OE WT 9-12 cells. (F) Gene ontology analysis of CDYL and PanKcr coregulated genes.