Table 3:
HPV testing and histologic outcomes of Pap tests from transmasculine individuals receiving testosterone from this cohort and the literature
| Study | Current study | Adkins et al (2018) | Williams et al (2020) | Plummer et al (2021) | |||
|---|---|---|---|---|---|---|---|
|
| |||||||
| Cytology | Histology | Cytology | Histology | Cytology* | Cytology | Histology | |
|
| |||||||
| HPV-positive cases | 2 NILM | 1 benign/1 no FU | 1 NILM | 1 benign | 1 NILM | 4 NILM | 1 benign/3 no FU |
| 2 ASC-US | 2 HSIL | 1 ASC-US/1 ASC-H | 1 no FU/1 LSIL | 1 ASCUS | 1 LSIL | ||
| 2 HSIL | 2 HSIL | 1 HSIL | 1 HSIL | ||||
|
| |||||||
| HPV-negative cases | 22 NILM | 12 benign/10 no FU | 6 NILM | 6 benign | 3 NILM | 16 NILM | 6 benign/10 no FU |
| 1 ASC-US | 1 benign | 2 ASC-US | 2 benign | 1 ASC-US | 2 ASC-US/1 AGC | 2 benign/1 LSIL | |
| 3 UNSAT | 1 benign/2 no FU | 4 UNSAT | 4 benign | ||||
|
| |||||||
| HPV-positive rate | 6/32 (19%) | 4/12 (33%) | 1/5 (20%) | 5/27 (18.5%) | |||
no histologic outcome available according to HPV testing;
NILM: negative for intraepithelial lesion or malignancy; FU: follow-up; ASCUS: atypical squamous cells of undetermined significance; HSIL: high-grade squamous intraepithelial lesion; LSIL: low-grade squamous intraepithelial lesion; ASC-H: atypical squamous cells of undetermined significance, cannot rule out HSIL; AGC: atypical glandular cells; UNSAT: unsatisfactory