Figure 3.
Baseline microvascular mitochondrial membrane potential, oxygenation, and ATP levels. Mitochondrial membrane potential (ΔΨM) was significantly attenuated with aging, restored with SVF therapy (A). There was no difference between groups in oxygen MFI (note: BioTracker 520 increases MFI with decreasing oxygen; B). ATP was not reduced with aging but was significantly enhanced with SVF therapy compared with OC (C). Significance as *P < 0.05 with one-way ANOVA and Bonferroni post hoc analysis. Scale bar = 100 μm. MFI, mean fluorescence intensity; OC, old control; SVF, stromal vascular fraction.