Figure 6.
Concentration of CXCL1/KC (A), CXCL2/MIP2 (B), tumor necrosis factor-α (TNFα; C), and interleukin-6 (IL-6; D) in whole lung homogenates obtained from natriuretic peptide receptor-C wild-type (NPR-C+/+) and knockout (NPR-C−/−) mice treated with infusion of saline followed by oropharyngeal aspiration of saline (NaCl/NaCl), infusion of saline and oropharyngeal aspiration of Pseudomonas aeruginosa (PA103; NaCl/PA103), infusion of atrial natriuretic peptide (ANP) followed by oropharyngeal aspiration of saline (ANP/NaCl), or infusion of ANP followed by oropharyngeal aspiration of PA103 (ANP/PA103). n = 6 mice for each condition and genotype. *P < 0.05.