Table 7.
KEGG pathways enriched in DEGs from the skeletal muscle of female OB-fetuses
Pathway | Input No. | Total No. | P Value |
---|---|---|---|
Aminoacyl-tRNA biosynthesis | 6 | 66 | 3.05e-04 |
RNA transport | 8 | 167 | 9.23e-04 |
MAPK signaling pathway | 10 | 294 | 1.71e-03 |
Endocytosis | 9 | 270 | 3.64e-03 |
mTOR signaling pathway | 6 | 155 | 1.22e-02 |
Protein processing in endoplasmic reticulum | 6 | 163 | 1.49e-02 |
Cortisol synthesis and secretion | 4 | 69 | 1.70e-02 |
Adipocytokine signaling pathway | 4 | 71 | 1.81e-02 |
Ras signaling pathway | 7 | 233 | 1.85e-02 |
Biosynthesis of amino acids | 4 | 78 | 2.30e-02 |
Regulation of actin cytoskeleton | 6 | 217 | 4.16e-02 |
PI3K-Akt signaling pathway | 8 | 358 | 4.19e-02 |
Wnt signaling pathway | 5 | 162 | 4.86e-02 |
DEGs, differentially expressed genes; mTOR, mechanistic target of rapamycin; OB, obese.