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. 2022 Sep 29;39(19-20):1349–1362. doi: 10.1089/neu.2022.0026

Table 5.

PoCS Rule Performance for Prediction of PPCS (90 Days)

 
Derivation cohort (n = 471)
Validation cohort (n = 602)
Post-concussion symptoms, n (%) 71 (15.1) 96 (15.9)
Using threshold ≥2 points 7 days after trauma % 95% CI§ % 95% CI§
Sensitivity 91.4 (84.9-98.0) 89.6 (83.5-95.7)
Specificity 53.8 (48.7-58.9) 44.7 (40.3-49.0)
Negative predictive value 97.2 (94.9-99.4) 95.8 (93.2-98.3)
Positive predictive value 26.6 (21.0-32.1) 23.5 (19.2-27.8)
Using threshold ≥3 points 7 days after trauma        
Sensitivity 87.1 (79.3-95.0) 86.5 (79.6-93.3)
Specificity 66.7 (61.9-71.5) 56.1 (51.8-60.5)
Negative predictive value 96.6 (94.4-98.8) 95.6 (93.3-97.9)
Positive predictive value 32.4 (25.7-39.1) 27.2 (22.2-32.2)
§

95% Confidence interval.

For 10 medium risk patients, data were missing for at least one predictor at follow-up evaluation.

PoCS, Post-Concussion Symptoms Rule; PPCS, persistent post-concussion symptoms; CI, confidence interval.