Table 1.
Two-Week Cross-Sectional Diffusion Tensor Imaging of Patients with Mild Traumatic Brain Injury and Controls
Tract | Fractional Anisotropy |
Axial Diffusivity 10−3 mm2/sec |
Mean Diffusivity 10−3 mm2/sec |
Radial Diffusivity 10−3 mm2/sec |
||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
mTBI | Controls | Cohen d | mTBI | Controls | Cohen d | mTBI | Controls | Cohen d | mTBI | Controls | Cohen d | |
Global | 0.430 ± 0.026 | 0.434 ± 0.026 | 0.164 | 1.105 ± 0.046 | 1.086 ± 0.050 | -0.394** | 0.732 ± 0.030 | 0.715 ± 0.037 | -0.537** | 0.545 ± 0.029 | 0.531 ± 0.035 | -0.442** |
GCC | 0.676 ± 0.039 | 0.656 ± 0.049 | -0.437** | 1.519 ± 0.071 | 1.451 ± 0.083 | -0.878** | 0.769 ± 0.049 | 0.754 ± 0.046 | -0.328** | 0.399 ± 0.055 | 0.404 ± 0.057 | 0.101 |
BCC | 0.642 ± 0.037 | 0.646 ± 0.041 | 0.110 | 1.566 ± 0.062 | 1.496 ± 0.078 | -0.995** | 0.831 ± 0.047 | 0.796 ± 0.049 | -0.712** | 0.467 ± 0.055 | 0.441 ± 0.055 | -0.465** |
SCC | 0.757 ± 0.034 | 0.753 ± 0.033 | -0.119 | 1.530 ± 0.054 | 1.474 ± 0.067 | -0.917** | 0.719 ± 0.042 | 0.699 ± 0.039 | -0.513** | 0.315 ± 0.050 | 0.309 ± 0.044 | -0.109 |
ALIC | 0.549 ± 0.033 | 0.545 ± 0.033 | -0.125 | 1.224 ± 0.067 | 1.147 ± 0.077 | -1.066** | 0.716 ± 0.040 | 0.681 ± 0.034 | -0.947** | 0.467 ± 0.041 | 0.444 ± 0.028 | -0.655** |
PLIC | 0.666 ± 0.031 | 0.678 ± 0.032 | 0.367** | 1.305 ± 0.075 | 1.236 ± 0.075 | -0.926** | 0.681 ± 0.038 | 0.643 ± 0.039 | -0.998** | 0.372 ± 0.035 | 0.342 ± 0.036 | -0.843** |
ACR | 0.461 ± 0.032 | 0.457 ± 0.032 | -0.125 | 1.139 ± 0.060 | 1.094 ± 0.067 | -0.694** | 0.727 ± 0.037 | 0.706 ± 0.038 | -0.543** | 0.525 ± 0.038 | 0.509 ± 0.035 | -0.435** |
SCR | 0.481 ± 0.027 | 0.486 ± 0.027 | 0.173 | 1.101 ± 0.060 | 1.039 ± 0.060 | -1.019** | 0.691 ± 0.036 | 0.657 ± 0.035 | -0.965** | 0.490 ± 0.035 | 0.462 ± 0.032 | -0.869** |
PTR | 0.570 ± 0.040 | 0.581 ± 0.036 | 0.294* | 1.328 ± 0.054 | 1.278 ± 0.067 | -0.812** | 0.768 ± 0.039 | 0.736 ± 0.043 | -0.780** | 0.489 ± 0.047 | 0.461 ± 0.045 | -0.615** |
EC | 0.406 ± 0.037 | 0.398 ± 0.034 | -0.247 | 1.139 ± 0.047 | 1.075 ± 0.059 | -1.209** | 0.771 ± 0.031 | 0.739 ± 0.036 | -0.944** | 0.590 ± 0.040 | 0.567 ± 0.038 | -0.591** |
CGC | 0.509 ± 0.044 | 0.504 ± 0.042 | -0.109 | 1.221 ± 0.065 | 1.151 ± 0.080 | -0.953** | 0.746 ± 0.041 | 0.711 ± 0.044 | -0.816** | 0.511 ± 0.048 | 0.488 ± 0.046 | -0.495** |
SLF | 0.478 ± 0.029 | 0.480 ± 0.028 | 0.079 | 1.104 ± 0.042 | 1.054 ± 0.052 | -1.040** | 0.701 ± 0.026 | 0.673 ± 0.031 | -0.951** | 0.502 ± 0.032 | 0.479 ± 0.032 | -0.705** |
SFO | 0.445 ± 0.036 | 0.454 ± 0.035 | 0.268* | 1.040 ± 0.068 | 0.983 ± 0.076 | -0.798** | 0.671 ± 0.045 | 0.637 ± 0.044 | -0.770** | 0.492 ± 0.045 | 0.459 ± 0.040 | -0.762** |
PCR | 0.467 ± 0.029 | 0.471 ± 0.030 | 0.133 | 1.179 ± 0.043 | 1.127 ± 0.063 | -0.969** | 0.755 ± 0.031 | 0.726 ± 0.042 | -0.812** | 0.546 ± 0.035 | 0.521 ± 0.041 | -0.655** |
SS | 0.515 ± 0.036 | 0.522 ± 0.036 | 0.183 | 1.271 ± 0.055 | 1.219 ± 0.068 | -0.845** | 0.777 ± 0.033 | 0.746 ± 0.039 | -0.874** | 0.533 ± 0.040 | 0.505 ± 0.041 | -0.678** |
mTBI, mild traumatic brain injury; GCC, genu of the corpus callosum; BCC, body of the corpus callosum; SCC, splenium of the corpus callosum; ALIC, anterior limb of the internal capsule; PLIC, posterior limb of the internal capsule; ACR, anterior corona radiata; SCR, superior corona radiata; PTR, posterior thalamic radiation; EC, external capsule; CGC, dorsal cingulate bundle; SLF, superior longitudinal fasciculus; SFO, superior fronto-occipital fasciculus; PCR, posterior corona radiata; SS, sagittal stratum.
Bold: p < 0.05; *p < 0.01; **p < 0.001.
Diffusion tensor imaging metric values: mean ± standard deviation; Cohen d is positive for Controls > mild traumatic brain injury.