Figure 2.

miR-331-3p can inhibit the proliferation, migration, and invasion of OS in vitro. (a) 143b and Hos are transfected with miR-331-3p mimics or inhibitors, and then cell biological functions are evaluated. (a) qRT-PCR detects the transfection efficiency of miR-331-3p. (b) The cell viability of 143b and Hos after the detection of miR-331-3p mimics/inhibitors by CCK-8. (c) Colony formation analysis of changes in OS cell proliferation ability. (d) The transwell experiment detects the invasion level of OS cells. (e) The migration ability of OS cells is analyzed by wounding experiments. The results are shown as the mean ± standard deviation (SD) from three independent experiments. ^∗∗P < 0.01.