Table 2.
Studies on ablation therapy for liver metastasis from colorectal cancer
| Author | Publication year | Type of ablation | No. of patients | No. of tumors | Size of Tumors [mm] | Follow-up [months] | Local tumor control [%] | Overall survival [months] | Overall survival [%] (Disease- or Progression-free survival [%]) |
||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1-year | 2-year | 3-year | 4-year | 5-year | |||||||||
| Cheng et al. [11] | 2021 | RFA | 68 | – | 29 (median) | 59.8 (median) | 47.1 | 53.4 (median) | 88.1 | – | 66.9 | – | 64.5 |
| Knott et al. [12] | 2021 | MWA | 57 | 102 | 18 (mean) | 42 (median) | 96 | 52 (median) |
96 (93) |
– |
66 (58) |
– |
47 (39) |
| Fan et al. [13] | 2021 | RFA | 199 | 402 | 16 (mean) | 23 (median) | 62.9 |
Subcapsular 46 (median) |
96.1 | – | 66 | – | 44.2 |
|
non-subcapsular 60 (median) | |||||||||||||
| Kurilova et al. [14] | 2021 | RFAa MWA | 286 | 415 | – | 31 (median) | – | 41.5 (median) |
91 (67) |
72 (55) |
53 (47) |
– | 37 |
| Han et al. [9] | 2021 | RFA | 365 | 512 | – | 43.1(median) | 75.4 | 44 (median) |
92 (85) |
– |
58 (74) |
– |
41 (73) |
| Wang et al. [15] | 2020 | RFA | 85 | 138 | 28 (mean) | 30 (median) | 67.4 | 36 (median) | 90.6 | – | 45.6 | – | 22.9 |
| Thai et al. [16] | 2020 | RFA | 61 | 166 | – | 24 (median) | 88.5 | 32 (median) | 93.2 | – | 44.5 | – | 38.2 |
| Wang et al. [17] | 2020 | RFA | 81 | 126 | 25(mean) | 51.2 (median) | 52.8 | 26.8 (median) |
81.2 (59.3) |
(51.4) |
32.1 (46.6) |
– | 23.9 |
| Jiang et al. [10] | 2020 | RFA | 104 perivascular group | 388 | 24 (mean) | 45.0 (median) | 82.7 | – |
91.3 (85.2) |
– |
45.6 (81.1) |
– |
23.9 (81.1) |
| 284 non-perivascular group | 85.2 | – |
85 (88.8) |
– |
51.9 (80.3) |
– |
25.6 (78.6) |
||||||
| Mao et al. [18] | 2019 | RFA | 61 | 114 | 27 (median) | 28.9 (median) | 83.3 | – | – | – | (70.9) | – | 33 |
| Ou et al. [19] | 2018 | RFA | 109 | 109 | 34 (mean) | 26 (median) | – | 56.5 (mean) | 92.3 | – | 50.7 | – | 41.6 |
| Shady et al. [20] | 2017 | RFA | 97 | – | 17 (median) | 60.1 (median) | 56.1 | 35.5 (median) |
89.6 (68.8) |
– |
48.5 (50.1) |
– |
30.3 (47.3) |
| Facciorusso et al. [21] | 2016 | RFA | 127 | 193 | 27 (median) | 63 (median) | 79.5 | 38 (median) | 89.4 | – | – | 40.4 | 33.3 |
| Shady et al. [22] | 2016 | RFA | 162 | 233 | 18 (median) | 55 (median) | 52 | 36 (median) | 90 | – | 48 | – | 31 |
| Facciorusso et al. [23] | 2016 | RFA | 143 | – | 26 (median) | 72 (median) | 81.1 | 44 (median) | 91.4 | – | – | 46.5 | 42.2 |
| Zhang et al. [24] | 2016 | MWA | 199 | 318 | 30 (median) | 30.2 (median) | 94.9 | 41 (median) | – | – | – | – |
27.9 (10.1) |
| Labori et al. [25] | 2015 | RFA | 52 | 70 | – | – | – | 36 (median) | – | – | – | – | 27 |
| Hamada et al. [26] | 2012 | RFA | 84 | 141 | 23(mean) | 27.0 (median) | 72.3 | 34.9 (median) |
90.6 (73.7) |
– |
44.9 (55.1) |
– |
20.8 (47.2) |
| Solbiati et al. [8] | 2012 | RFA | 99 | 202 | 22 (mean) | 72 (median) | 67.7 | 53 (median) | 98 | – | 69.3 | – | 47.8 |
| Veltri et al. [27] | 2012 | RFA | 248 | 458 | – | 26.4 (mean) | – | 32 (median) | 84 | 59 | 43 | – | 23 |
aRFA and MWA were used for 56% and 44% of sessions, respectively
RFA radiofrequency ablation, MWA microwave ablation