Table 3:
Gene expression level of 19 Crohn’s disease patients during flare/remission
| Tests | Disease stage (No. of patients) | P value | ||
|---|---|---|---|---|
|
| ||||
| Inactive (8) (mean ± SD) | Active (11) (mean ± SD) | |||
| IL10 | Phase 1 | 1.31 ± 1.03 | 6.36 ± 7.03 | 0.003 |
| Phase 2 | 0.78 ± 1.1 | 0.99 ± 1.32 | 0.2 | |
| TNF-α | Phase 1 | 1.59 ± 1.33 | 4.69 ± 3.08 | 0.004 |
| Phase 2 | 0.95 ± 0.82 | 0.81 ± 0.81 | 0.5 | |
| IFN-ϒ | Phase 1 | 1.14 ± 1.01 | 6.78 ± 4.62 | 0.003 |
| Phase 2 | 1.28 ± 1.45 | 1.18 ± 0.78 | 0.8 | |
| Foxp3 | Phase 1 | 1.09 ± 0.32 | 1.04 ± 0.34 | 0.1 |
| Phase 2 | 0.91 ± 0.18 | 1.51 ± 0.57 | 0.008 | |
Values are means ± standard deviations (SD). Data represent units obtained with the RT-qPCR normalized to actB. P < 0.05 means statistically significant differences