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. Author manuscript; available in PMC: 2023 Oct 4.
Published in final edited form as: Circulation. 2022 Aug 25;146(14):1033–1045. doi: 10.1161/CIRCULATIONAHA.121.056719

Figure 3. Elevated cell-free DNA (cfDNA) concentrations are associated with lower transplant-free survival in Cohort B pulmonary arterial hypertension (PAH) patients.

Figure 3.

Kaplan-Meier analysis over a median (IQR) follow up time of 2.7 (1.0–5.2) years demonstrated significantly different transplant-free survival amongst cfDNA tertiles (log-rank test: P=0.0001). Corresponding concentrations for each cfDNA tertile are as follows: ≤ 28.99 ng/ml (blue line), 28.99 < cfDNA ≤ 61.12 ng/ml (red line), and > 61.12 ng/ml (green line). Patients were censored at the time of death or transplantation.