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. Author manuscript; available in PMC: 2023 Oct 4.
Published in final edited form as: Circulation. 2022 Aug 25;146(14):1033–1045. doi: 10.1161/CIRCULATIONAHA.121.056719

Figure 4. Receiver operating characteristic analyses of REVEAL 2.0 risk and REVEAL 2.0 risk with the addition of cell-free DNA (cfDNA) for predicting death or lung transplant in Cohort B.

Figure 4.

After adjusting for both age and sex, the area under the curve (AUC) of receiver operating characteristics for REVEAL 2.0 risk categories (blue line) was similar to the performance of cfDNA tertiles (line not shown) in Cohort B (AUC of 0.72 versus 0.75; P=0.29). The predictive performance of REVEAL 2.0 risk classification significantly improved with the addition of cfDNA tertiles (red line), with the AUC increasing from 0.72 to 0.78 (P=0.02).