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. 2022 Oct 3;12:16552. doi: 10.1038/s41598-022-20420-3

Table 1.

Baseline demographic and clinical characteristics of the patients.

Demographic information Pooled Cohorta
(n = 242)
Age (years) 50.8 ± 9.2
Years of education 11.2 ± 3.4
Body mass index (kg/m2) 24.5 ± 4.3
Ethnicity Chinese 203 (83.9)
Malay 23 (9.5)
Indian 9 (3.7)
Others 7 (2.9)
Breast cancer stage I 31 (12.8)
II 153 (63.2)
III 58 (24.0)
ECOG status 0 229 (94.6)
1 13 (5.4)
Chemotherapy regimen Anthracycline-based 166 (68.6)
Taxane-based 76 (31.4)
Menopausal status Pre-menopausal 122 (50.4)
Post-menopausal 120 (49.6)
Estradiol (pM) 191.9 ± 232.2
DHEAS (µM) 2.8 ± 1.9
DHEA (nM) 14.5 ± 10.9
Baseline fatigue scoresb 1.7 ± 1.8
Baseline anxiety scoresc 6.8 ± 6.9
Baseline insomnia scoresd 21.7 ± 26.1

aData are presented as mean ± standard deviation for continuous variables and frequency (%) for categorical variables.

bFatigue scores are out of maximum of 10 points, with higher score indicating greater extent of fatigue. cAnxiety scores are out of maximum of 63 points, with higher score indicating greater extent of anxiety. dInsomnia scores are out of maximum of 100 points, with higher score indicating greater extent of insomnia.