Figure 2.

A diagram of the image analysis process, starting from the initial acquired spin density maps to the RBC and TP exchange maps, correcting for imperfect selection of the targeted resonance. For each of the 5 saturation frequencies, two images are acquired during breath-holds following ventilation with Xe/O2 gas mixture. Post/pre-saturation ratios are taken for each frequency, and lastly, these ratio maps are divided by either the ratios maps of the opposing resonance saturation frequency (dRBC,corr) or the control measurement to yield the corrected compartment-specific GP depolarization maps dRBC,corr or dTP,corr, respectively.