Fig. 2. Schematic illustrating the process of reconstructing white matter tracts between regions involved in particular facets of socio-affective processing.

a Meta-analysis-based images of brain regions associated with a particular facet of socio-affective processing (e.g., mirroring) were generated by submitting sets of keywords (e.g., action observation, mirror neuron, mirror) to Neurosynth²². b These images were aggregated across terms in a set, and discrete regions of interest were identified. c For each subject, probabilistic tractography was then conducted to trace white matter tracts (colored lines in this schematic image) connecting each pair of brain regions (red nodes). This procedure was repeated to construct the affective processing, mentalizing, and face perception networks (see Methods for further details).