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. 2022 Oct 3;5:1051. doi: 10.1038/s42003-022-03932-6

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — RNA-sequencing-based expression levels (measured in transcripts per million, TPM, and represented as median and interquartile range) are highest in cornea, trabecular meshwork (TM), and sclera in human (a), and African green monkey (b) eyes, and in cornea, TM, sclera, optic nerve head, and choroid/RPE in C57BL/6 J mouse eyes (c); In situ hybridization (RNAscope) shows ANGPTL7/Angptl7 (red) expression in TM, cornea and sclera in human (d) and murine (e) eyes. Scale bars represent 100 μm. DAPI staining (blue) counterstains cell nuclei. RPE retinal pigmented epithelium, CB ciliary body, SC Schlemm’s canal, CM ciliary muscle, AC anterior chamber, RGC retinal ganglion cell, INL inner nuclear layer, ONL outer nuclear layer.