Table 1.
HPTN 082 participant characteristics at baseline (N=427, unless otherwise indicated)1
| Baseline characteristics | Overall | By HIV Risk Group2 |
||
|---|---|---|---|---|
| Any HIV Risk (N=364; 85%) | No HIV Risk (N=63; 15%) | p-value3 | ||
|
| ||||
| Arm | 0.84 | |||
| Standard package | 212 (50%) | 180 (50%) | 32 (51%) | |
| Standard package plus drug-level feedback counseling | 215 (50%) | 184 (51%) | 31 (49%) | |
|
| ||||
| Study site | 0.094 | |||
| Johannesburg, South Africa | 142 (33%) | 124 (34%) | 18 (29%) | |
| Cape Town, South Africa | 140 (33%) | 124 (34%) | 16 (25%) | |
| Harare, Zimbabwe | 145 (34%) | 116 (32%) | 29 (46%) | |
|
| ||||
| Age, years | 21.0 (19.0-22.0) | 21.0 (19.0-22.0) | 22.0 (20.0-23.0) | 0.13 |
|
| ||||
| Education | 0.86 | |||
| Primary school | 9 (2%) | 8 (2%) | 1 (2%) | |
| Secondary school | 371 (87%) | 317 (87%) | 54 (86%) | |
| College or university | 47 (11%) | 39 (11%) | 8 (13%) | |
|
| ||||
| Likely depression (N=418)4 | 259 (62%) | 221 (61%) | 38 (60%) | 0.72 |
|
| ||||
| Social support (N=423)5 | 3.0 (2.0-4.0) | 3.0 (2.0-4.0) | 3.0 (2.0-3.0) | 0.21 |
|
| ||||
| Stigma (N=422)6 | 6.0 (1.0-7.0) | 6.0 (1.0-7.0) | 6.0 (3.0-8.0) | 0.63 |
|
| ||||
| Any intimate partner violence (N=424)7 | 209 (49%) | 183 (50%) | 26 (43%) | 0.26 |
|
| ||||
| Any posttraumatic stress disorder symptoms (N=418)8 | 194 (46%) | 165 (46%) | 29 (50%) | 0.55 |
Data are presented as median (interquartile range) for continuous variables and frequency (percentage) for categorical variables
Any HIV risk was defined as reporting at least one of the following at a given study visit: condomless vaginal or anal sex with condoms; reporting a primary partner living with HIV who was not known to be taking antiretrovirals; reporting a primary partner with unknown HIV status; more than one sexual partner; any STI diagnosis; reporting transactional sex; reporting drug and/or alcohol use before or during sex
p-values are based on Wilcoxon rank sum test for continuous variables and χ2 test for categorical variables
A sum CESD-10 score ≥10 was indicative of “likely depression”
Social support was measured as the sum score across two items assessing social support from adults and close friends (range: 0-4)
Stigma was measured as the sum score across ten items assessing stigma related to HIV and PrEP use (range: 0-40)
Participants were considered to have experienced any intimate partner violence if they endorsed at least one of four items asking about recent physical, emotional, or sexual violence from a sexual partner
A response of “yes” to any of four items from the Posttraumatic Stress Disorder (PTSD) Checklist for the DSM-5 (PCL-5) was indicative of PTSD symptoms