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. 2022 Oct 3;12:428. doi: 10.1038/s41398-022-02172-w

Table 2.

Summary statistics from GWAS studies.

Reference Phenotype Dataset Sample size SNP h2
Nagel et al. 2018 [60] Neuroticism UK Biobank & PGC 390,279 0.10
Levey et al. 2020 [61] GAD Million Veteran Program 199,611 0.056
Okbay et al. 2016 [62] SWB Meta-analysis across 59 cohorts 298,420 0.040
Howard et al. 2019 [63] MDD UK Biobank & PGC 500,199 0.11
Levey et al. 2021 [64] Million Veteran Program 250,215
Linnér et al. 2019 [65] Risk-taking UK Biobank 431,126 0.050
Doherty et al. 2018 [48] Physical activities UK Biobank 91,105 0.10–0.21

GAD general anxiety disorder, SWB subjective well-being, MDD major depressive disorder, PGC Psychiatric Genetics Consortium.