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. 2022 Oct 3;13(10):845. doi: 10.1038/s41419-022-05291-w

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — A DHRS2 protein expression levels of in OVCAR3-CON, OVCAR3-DHRS2, HO-8910-CON, HO-8910-DHRS2, SKOV3-shCON, and SKOV3-shDHRS2 cells. B Cell viability of the designated groups was detected by MTS assay. C Foci formation ability of the designated groups was determined by colony formation assay. D Cells were seeded in the upper chamber with Matrigel coating for 72 h, and cell invasion ability of the designated group was determined. Data are shown as mean values ± S.D. of independent, triplicate experiments. The asterisks (*,**,***) indicate significant differences (p < 0.05, p < 0.01, p < 0.001, respectively).