Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Oct 3;13(10):845. doi: 10.1038/s41419-022-05291-w

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 4 — A The protein expression levels of CHKα in the designated group. After treated with 10 μM choline for 3 days or transfection with CHKα, B the viability of the cells was detected by MTS, C the invasive capability of the cells was determined by cell invasion assay, and D the protein levels of p-AKT and perilipin1 were detected by Western blotting. E–G After treated with actinomycin D (5 μg/ml), CHKα mRNA levels were measured by RT-qPCR, and the percentage of remaining mRNAs in the designated group were plotted. H RIP assay showing that DHRS2 can bind to CHKα mRNA in both OVCAR3 and HO-8910 cells. Data are shown as mean values ± S.D. of independent, triplicate experiments. The asterisks (*,**,***) indicate significant differences (p < 0.05, p < 0.01, p < 0.001, respectively).