Figure 3.

Wild-type (WT) S peptide pool-specific interferon-γ (IFN-γ)⁺ CD4⁺ and CD8⁺ T cells after COVID-19 vaccination by disease category. (A) and (B) show S-specific IFN-γ⁺ CD4⁺ and CD8⁺ results respectively in five disease categories (combined, humoral, innate, dysregulation and phagocytic) after 2 doses, while C and D show S-specific IFN-γ⁺ CD4⁺ and CD8⁺ results after 3 doses. Geometric means (GM) are shown with center lines and stated above each column. Cut-offs were drawn as grey lines. Number of analyzed available samples (n) are also stated above each column. A and B included 1 patient (in combined) who received first 2 doses intradermally and their datapoints were shown as darkened squares. (C) and (D) also included 4 patients (1 each in combined, humoral, innate and dysregulation) who received their third dose intradermally and their datapoints were also shown as darkened squares.